Allergy Testing Edmonton

Allergy Testing Edmonton - Asthma literally means and translates to "panting" in the Greek language. It refers to a chronic inflammatory disease of the airways and lungs. The characteristic asthma symptoms are recurring and variable, including reversible airflow obstruction and bronchospasm. Signs of asthma consist of: chest tightness, wheezing, shortness of breath and coughing. Asthma is clinically classified depending on the frequency of signs, peak expiratory flow rate and forced expiratory volume in one second. Asthma may be further categorized as atopic or extrinsic or non-atopic or intrinsic.

The condition of asthma is triggered by various genetic and environmental elements or combination there of. Acute signs are normally treated by making use of an inhaled short-acting beta-2 agonist like salbutamol. Individuals who suffer from asthma try to avoid triggers including allergens and irritants. Those who suffer from asthma normally find relief by inhaling corticosteroids. Treatments making use of Leukotriene antagonists are less useful than corticosteroids are usually less preferred.

Normally, a diagnosis is made based upon the pattern of indications in addition to the response to therapy over time. Ever since the 1970s, there has been a significant increase in asthma. Based on the 2010 statistics, across the globe, more than three hundred million people are affected worldwide and 250,000 asthma deaths were recorded in 2009. The prognosis for asthma is generally good because of the ability to correctly handle this condition with therapy.


The classification of asthma is based upon its severity in individuals, the frequency of signs, if the symptoms happen at night, FEV1 variability and predicted percent of FEV1, how often and intermittent the attacks take place. The asthma may be considered mild persistent if the attacks take place less than 2 times a week and not every day. For instance, if they happen 3 to 4 times a month. Another category will be moderate persistent. These attacks can take place once a week but not nightly. Daily attacks are considered to be severe persistent taking place usually 7 times per week, maybe a number of times per day.

Presently, there is no concise method for categorizing various subgroups of asthma, even if the condition is classified based on severity as listed above. Cases of asthma respond to various treatments. There is still much research ongoing to find ways to classify subgroups and which treatments respond well.

Asthma is not classed as a chronic obstructive pulmonary diseases, though this sickness is a chronic obstructive condition. Chronic obstructive pulmonary disease comprise emphysema, chronic bronchitis and bronchiectasis for example. These diseases are irreversible. In asthma, the airway obstruction is reversible, however, if not treated, the chronic lung inflammation during asthma could become an irreversible obstruction due to airway remodeling. Asthma even affects the bronchi and not the alveoli as in emphysema.

Asthma Attack

Asthma attacks are defined as an acute asthma exacerbation. The classic signs comprise: wheezing, chest tightness and shortness of breath, though several people present mainly together with coughing. In some cases, are motion could be impaired so greatly that no wheezing is heard. During an attack, there may be a paradoxical pulse, which means a pulse which is weaker during inhalation and stronger during exhalation. The individual might have a blue tinge to their skin and nails resulting from lack of oxygen. Certain neck muscles like for example the sternocleidomastoid and scalene muscles may become more pronounced as the person struggles for air.

The peak flow rate or PEFR is =200 L/min or =50% of the best possible flow rate in a mild exacerbation. Moderate is defined as between 80 and 200 L/min or 25 percent and 50 percent of the predicted best while severe is defined as = 80 L/min or =25% of the predicted best.

Exercise Induced

Among top athletes, asthma could be induced by exercise. In the 1996 Summer Olympic Games in Atlanta, a study of the athletes showed that 15% of athletes had asthma and 10% were on asthma medication. The most common sports which have a high occurrence of asthma consist of long-distance running, mountain biking and cycling. Diving and weight-lifting show a fairly lower occurrence. There has been evidence suggesting insufficient levels of vitamin D are associated with serious asthma attacks. Usually, exercise induced asthma is treated effectively utilizing a short-acting beta2 agonist.

Occupational Asthma

Many people suffer from asthma as because of things they are exposed to at their office. This is reported as occupational respiratory disease. The majority of cases of occupational asthma are not reported or recognized as such. The highest percentage of cases occurred during labourers and fabricators, followed by professional and managerial specialists as well as those in sales, administrative support and technical jobs. The majority of these cases of asthma were in the services and manufacturing businesses. Certain reactive chemicals are commonly associated with work-related asthma as well as things like enzymes, animal proteins, natural rubber latex and flour. One study reported that 15-23% of new onset asthma cases that happened in adults are work related.


Asthma is caused by environmental and genetic elements. These issues influence how severe the asthma is as well as how it responds to medication. There have been researches showing associated illnesses like hay fever and eczema are related. The strongest risk factor for developing asthma is a history of atopic disease. The more allergens an individual reacts to on a skin test, the higher the odds of them having asthma.

Much of the allergic reactions to asthma is likewise connected with sensitivities to indoor allergens. The normal style of housing in the west, would likewise allow greater exposure to indoor allergens. There have been mixed findings to the prevention studies aimed at the aggressive reduction of airborne allergens inside a home with infants. Like for instance, strict dust mite restriction has lessened the risk of allergic sensitization to dust mites and moderately reduces the risk of developing asthma until the age of 8. Although, similar studies with exposure to cat and dog allergies have shown that exposure during the first year of life was found to lessen the risk of allergic sensitization and of developing asthma later in life.

There have been studies within the UK and the USA exploring the link between the development of asthma and obesity. Various factors related with obesity can play a role in the pathogenesis of asthma. Like for instance, because of a build-up of fatty or adipose tissue, a decreased respiratory function can occur. This may be partly because adipose tissue contributes to a pro-inflammatory condition and this has been related with non-eosinophilic asthma. Adult onset asthma has also been connected with periocular xanthogranulomas and Churg-Strauss syndrome.

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